Metabolism-2002Hoe

File Name : Metabolism-2002Hoe.eml

• Summary

  Stepper List (1)

  • DE

  System List (2)

  • /
  • /compartment

  Variable List (22)

  • /compartment:ADP
  • /compartment:ATP
  • /compartment:Ac
  • /compartment:AcCoA
  • /compartment:AcLac
  • /compartment:AcO
  • /compartment:AcP
  • /compartment:AcetoinIn
  • /compartment:AcetoinOut
  • /compartment:ActoinIn
  • /compartment:Butanediol
  • /compartment:CoA
  • /compartment:Dimensions
  • /compartment:EtOH
  • /compartment:NAD
  • /compartment:NADH
  • /compartment:O2
  • /compartment:Pi
  • /compartment:SIZE
  • /compartment:halfglucose
  • /compartment:lactate
  • /compartment:pyruvate

  Process List (14)

  • /:R1
  • /:R10
  • /:R11
  • /:R12
  • /:R13
  • /:R14
  • /:R2
  • /:R3
  • /:R4
  • /:R5
  • /:R6
  • /:R7
  • /:R8
  • /:R9
  
  
  

• Stepper

  
  

  Stepper Class/ID	Properties
  ODE45Stepper DE	# No Property	-----

  
  
  

• Detail Information

  System:/

  System Information
  StepperID	DE
  Name	Root System
  Variable List
  ID	Name		Value
  # No Property
  Process List
  Process Class/ID	Properties
  ExpressionFluxProcess R1
  	ID	R1
  	V_1	2397.0
  	Kglc_1	0.1
  	Knad_1	0.14
  	Kadp_1	0.047
  	Kpyr_1	25.0
  	Knadh_1	0.09
  	Katp_1	0.019
  	Expression	( V_1 (S2.MolarConc / Kglc_1) (S1.MolarConc / Knad_1) (S0.MolarConc / Kadp_1) / 1 + S2.MolarConc / Kglc_1 + P2.MolarConc / Kpyr_1) </em> (1 + S1.MolarConc / Knad_1 + P1.MolarConc / Knadh_1) <em> (1 + S0.MolarConc / Kadp_1 + P0.MolarConc / Katp_1[+] ) S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:ADP	-1
  		S1	Variable:/compartment:NAD	-1
  		S2	Variable:/compartment:halfglucose	0
  		P0	Variable:/compartment:ATP	1
  		P1	Variable:/compartment:NADH	1
  		P2	Variable:/compartment:pyruvate	1
  ExpressionFluxProcess R2
  	ID	R2
  	V_2	5118.0
  	Keq_2	21120.7
  	Kpyr_2	1.5
  	Knadh_2	0.08
  	Klac_2	100.0
  	Knad_2	2.4
  	Expression	( V_2 S1.MolarConc </em> S0.MolarConc - P1.MolarConc <em> P0.MolarConc / Keq_2) / (Kpyr_2 </em> Knadh_2[+] / 1 + S1.MolarConc / Kpyr_2 + P1.MolarConc / Klac_2) <em> (1 + S0.MolarConc / Knadh_2 + P0.MolarConc / Knad_2[+] ) S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:NADH	-1
  		S1	Variable:/compartment:pyruvate	-1
  		P0	Variable:/compartment:NAD	1
  		P1	Variable:/compartment:lactate	0
  ExpressionFluxProcess R3
  	ID	R3
  	V_3	259.0
  	Kpyr_3	1.0
  	Knad_3	0.4
  	Kcoa_3	0.014
  	Ki_3	46.4
  	Knadh_3	0.1
  	Kaccoa_3	0.008
  	Expression	( V_3 (S1.MolarConc / Kpyr_3) (S0.MolarConc / Knad_3) (S2.MolarConc / Kcoa_3) (S0.MolarConc / (S0.MolarConc + Ki_3 P0.MolarConc)) / 1 + S1.MolarConc / Kpyr_3) </em> (1 + S0.MolarConc / Knad_3 + P0.MolarConc / Knadh_3) <em> (1 + S2.MolarConc / Kcoa_3 + P1.MolarConc / Kaccoa_3[+] ) S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:NAD	-1
  		S1	Variable:/compartment:pyruvate	-1
  		S2	Variable:/compartment:CoA	-1
  		P0	Variable:/compartment:NADH	1
  		P1	Variable:/compartment:AcCoA	1
  ExpressionFluxProcess R4
  	ID	R4
  	V_4	42.0
  	Keq_4	0.0281
  	Kiaccoa_4	0.2
  	Kpi_4	2.6
  	Kipi_4	2.6
  	Kiacp_4	0.2
  	Kicoa_4	0.029
  	Kacp_4	0.7
  	Expression	( V_4 S0.MolarConc </em> S1.MolarConc - P1.MolarConc <em> P0.MolarConc / Keq_4) / (Kiaccoa_4 </em> Kpi_4[+] / (1 + S0.MolarConc / Kiaccoa_4 + S1.MolarConc / Kipi_4 + P1.MolarConc / Kiacp_4 + P0.MolarConc / Kicoa_4 + S0.MolarConc S1.MolarConc / (Kiaccoa_4 Kpi_4) + P1.MolarConc P0.MolarConc / (Kacp_4 Kicoa_4)) ) * S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:AcCoA	-1
  		S1	Variable:/compartment:Pi	0
  		P0	Variable:/compartment:CoA	1
  		P1	Variable:/compartment:AcP	1
  ExpressionFluxProcess R5
  	ID	R5
  	V_5	2700.0
  	Keq_5	174.2
  	Kadp_5	0.5
  	Kacp_5	0.16
  	Kac_5	7.0
  	Katp_5	0.07
  	Expression	( V_5 S1.MolarConc </em> S0.MolarConc - P1.MolarConc <em> P0.MolarConc / Keq_5) / (Kadp_5 </em> Kacp_5[+] / 1 + S1.MolarConc / Kacp_5 + P1.MolarConc / Kac_5) <em> (1 + S0.MolarConc / Kadp_5 + P0.MolarConc / Katp_5[+] ) S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:ADP	-1
  		S1	Variable:/compartment:AcP	-1
  		P0	Variable:/compartment:ATP	1
  		P1	Variable:/compartment:Ac	0
  ExpressionFluxProcess R6
  	ID	R6
  	V_6	97.0
  	Keq_6	1.0
  	Kaccoa_6	0.007
  	Knadh_6	0.025
  	Knad_6	0.08
  	Kcoa_6	0.008
  	Kaco_6	10.0
  	Expression	( V_6 S1.MolarConc </em> S0.MolarConc - P1.MolarConc <em> P0.MolarConc </em> P2.MolarConc / Keq_6) / (Kaccoa_6 <em> Knadh_6[+] / 1 + P0.MolarConc / Knad_6 + S0.MolarConc / Knadh_6) </em> (1 + S1.MolarConc / Kaccoa_6 + P1.MolarConc / Kcoa_6 + P2.MolarConc / Kaco_6 + P2.MolarConc <em> P1.MolarConc / (Kaco_6 </em> Kcoa_6[+] ) ) * S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:NADH	-1
  		S1	Variable:/compartment:AcCoA	-1
  		P0	Variable:/compartment:NAD	1
  		P1	Variable:/compartment:CoA	1
  		P2	Variable:/compartment:AcO	1
  ExpressionFluxProcess R7
  	ID	R7
  	V_7	162.0
  	Keq_7	12354.9
  	Kaco_7	0.03
  	Knadh_7	0.05
  	Knad_7	0.08
  	Ketoh_7	1.0
  	Expression	( V_7 S1.MolarConc </em> S0.MolarConc - P1.MolarConc <em> P0.MolarConc / Keq_7) / (Kaco_7 </em> Knadh_7[+] / 1 + P0.MolarConc / Knad_7 + S0.MolarConc / Knadh_7) <em> (1 + S1.MolarConc / Kaco_7 + P1.MolarConc / Ketoh_7[+] ) S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:NADH	-1
  		S1	Variable:/compartment:AcO	-1
  		P0	Variable:/compartment:NAD	1
  		P1	Variable:/compartment:EtOH	0
  ExpressionFluxProcess R8
  	ID	R8
  	V_8	600.0
  	Kpyr_8	50.0
  	Keq_8	9e+12
  	Kaclac_8	100.0
  	n_8	2.4
  	Expression	( V_8 S0.MolarConc / Kpyr_8 (1 - P0.MolarConc / (S0.MolarConc Keq_8)) (S0.MolarConc / Kpyr_8 + P0.MolarConc / Kaclac_8)^(n_8 - 1) / (1 + (S0.MolarConc / Kpyr_8 + P0.MolarConc / Kaclac_8)^n_8) ) * S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:pyruvate	-1
  		P0	Variable:/compartment:AcLac	2
  ExpressionFluxProcess R9
  	ID	R9
  	V_9	106.0
  	Kaclac_9	10.0
  	Kacet_9	100.0
  	Expression	( V_9 (S0.MolarConc / Kaclac_9) / (1 + S0.MolarConc / Kaclac_9 + P0.MolarConc / Kacet_9) ) S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:AcLac	-1
  		P0	Variable:/compartment:AcetoinIn	1
  ExpressionFluxProcess R10
  	ID	R10
  	V_10	200.0
  	Kacet_10	5.0
  	Expression	( V_10 (S0.MolarConc / Kacet_10) / (1 + S0.MolarConc / Kacet_10) ) S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:AcetoinIn	-1
  		P0	Variable:/compartment:AcetoinOut	1
  ExpressionFluxProcess R11
  	ID	R11
  	V_11	105.0
  	Keq_11	1400.0
  	Kacet_11	0.06
  	Knadh_11	0.02
  	Kbut_11	2.6
  	Knad_11	0.16
  	Expression	( V_11 S1.MolarConc </em> S0.MolarConc - P1.MolarConc <em> P0.MolarConc / Keq_11) / (Kacet_11 </em> Knadh_11[+] / 1 + S1.MolarConc / Kacet_11 + P1.MolarConc / Kbut_11) <em> (1 + S0.MolarConc / Knadh_11 + P0.MolarConc / Knad_11[+] ) S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:NADH	-1
  		S1	Variable:/compartment:AcetoinIn	-1
  		P0	Variable:/compartment:NAD	1
  		P1	Variable:/compartment:Butanediol	0
  ExpressionFluxProcess R12
  	ID	R12
  	V_12	900.0
  	Katp_12	6.2
  	n_12	2.6
  	Expression	( V_12 (S0.MolarConc / (P0.MolarConc Katp_12))^n_12 / (1 + (S0.MolarConc / (P0.MolarConc Katp_12))^n_12) ) S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:ATP	-1
  		P0	Variable:/compartment:ADP	1
  ExpressionFluxProcess R13
  	ID	R13
  	V_13	118.0
  	Knadh_13	0.041
  	Ko_13	0.01
  	Knad_13	1.0
  	Expression	( V_13 (S0.MolarConc S1.MolarConc / (Knadh_13 Ko_13)) / 1 + S0.MolarConc / Knadh_13 + P0.MolarConc / Knad_13) </em> (1 + S1.MolarConc / Ko_13[+] ) * S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:NADH	-1
  		S1	Variable:/compartment:O2	0
  		P0	Variable:/compartment:NAD	1
  ExpressionFluxProcess R14
  	ID	R14
  	k_14	0.0003
  	Expression	( k_14 S0.MolarConc ) S0.getSuperSystem().SizeN_A
  	VariableReferenceList
  		S0	Variable:/compartment:AcLac	-1
  		P0	Variable:/compartment:ActoinIn	1

  
  
  

  System:/compartment

  System Information
  StepperID	DE
  Variable List
  ID	Name		Value
  Dimensions	-----		3
  SIZE	-----		1.0
  ADP	-----		3.01106835e+24
  NAD	-----		6.0221367e+24
  ATP	-----		0.0
  NADH	-----		0.0
  pyruvate	-----		602213670000.0
  lactate	-----		6.0221367e+23
  CoA	-----		6.0221367e+23
  halfglucose	-----		1.80664101e+25
  AcCoA	-----		0.0
  Pi	-----		6.0221367e+24
  AcP	-----		0.0
  Ac	-----		6.0221367e+23
  AcO	-----		0.0
  EtOH	-----		6.0221367e+23
  AcLac	-----		0.0
  AcetoinIn	-----		0.0
  AcetoinOut	-----		0.0
  Butanediol	-----		6.0221367e+21
  O2	-----		1.20442734e+23
  ActoinIn	-----		0.0
  Process List
  Process Class/ID	Properties
  # No Property